GEL EXTRACTION OF EARTHWORMS (Lumbricus rubellus) TO THE NUMBER OF FIBROBAL CELLS IN MALE WISTAR RATS (Rattus norvegiccus) GINGIVAL WOUND HEALING

Introduction: Gingiva is one of the oral mucosa that most susceptible to injury, factors surgical procedures such as curettage which will be followed by a natural wound healing process. When occurs, cells act building blocks ground substance and formation collagen fibers in closing are fibroblast cells. Many people think earthworms (Lumbricus rubellus) only animal feed or fish feed, but have many properties antiperetic, antispasmodic, antidiuretic, antiasmatic, antihypertensive, antiallergic, anti-inflammatory, fibrinolytic activity. The purpose this study was determine effect application earthworm extract gel on number gingival process male Wistar (Rattus norvegicus) rats. Materials Methods : This research method used vivo laboratory experiments wistar rats with three treatment groups, namely group receiving 80% gel, control giving placebo (CMC-Na 2%) observed day 3. Results Discussion: results showed there significant difference mean score fibroblasts 3 group. given an concentration 418.67, while 270.33. Conclusion: It can concluded concentrate effective increasing rat wounds.